Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1174392 | 1.00 | — | — | |
| SCHEMBL1725970 | 0.96 | SMN1; SMN2 (0.61) | SMN1; SMN2TSHRALDH1A1KDM4ETP53 | |
| SCHEMBL28996592 | 0.92 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRALDH1A1KDM4ETP53 | |
| SCHEMBL26528341 | 0.92 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRALDH1A1KDM4ETP53 | |
| SCHEMBL65886 | 0.91 | SMN1; SMN2 (0.61) | SMN1; SMN2TSHRALDH1A1KDM4ELMNA | |
| SCHEMBL5483874 | 0.91 | SMN1; SMN2 (0.61) | SMN1; SMN2TSHRALDH1A1KDM4ETP53 | |
| SCHEMBL22878472 | 0.90 | SMN1; SMN2 (0.56) | SMN1; SMN2TSHRALDH1A1KDM4ETP53 | |
| SCHEMBL31292119 | 0.90 | SMN1; SMN2 (0.60) | SMN1; SMN2TSHRALDH1A1KDM4ETP53 | |
| SCHEMBL17284723 | 0.90 | SMN1; SMN2 (0.60) | SMN1; SMN2TSHRALDH1A1KDM4ETP53 | |
| Bromide SCHEMBL4607935 | 0.89 | SMN1; SMN2 (0.59) | SMN1; SMN2TSHRALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140273458-A1 | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-18 | — | — | US | claimed |
| EP-2779217-A2 | Chemical mechanical planarization for tungsten-containing substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-17 | — | — | EP | claimed |
| US-9700627-B2 | Biodegradable poly (beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-07-11 | — | — | US | disclosed |
| US-20160022821-A1 | BIODEGRADABLE POLY (BETA-AMINO ESTERS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-28 | — | — | US | disclosed |
| US-9101666-B2 | Biodegradable poly(beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-08-11 | — | — | US | disclosed |
| US-20140273458-A1 | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-18 | — | — | US | disclosed |
| EP-2779217-A2 | Chemical mechanical planarization for tungsten-containing substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-17 | — | — | EP | disclosed |
| US-8557231-B2 | Biodegradable poly(beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-10-15 | — | — | US | disclosed |
| WO-2009062742-A2 | POROUS SOLID ACID CATALYSTS, METHODS OF MANUFACTURING THE SAME, AND METHODS OF MANUFACTURING ORGANICS MOLECULES USING THE SAME | GRACE GMBH & CO. KG (DE) | 2009-05-22 | — | — | WO | disclosed |
| EP-0691150-A1 | Process for separating oil-in-water emulsions and basic polyamides therefor | BAYER AG (DE) | 1996-01-10 | — | — | EP | disclosed |
| US-4133844-A | POLYOLEFIN, N-VINYL-2-PYRROLIDONE POLYMER AND A POLYAMIDE CONTAINING TERTIARY AMINE NITROGENS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4126467-A | POLYMER HAVING REPEATING PIPERAZING-CONTAINING UNITS | FUJI PHOTO FILM CO., LTD. (JP) | 1978-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022821-A1 | BIODEGRADABLE POLY (BETA-AMINO ESTERS) AND USES THEREOF | PARN, PARG, NPEPPS | SMN1; SMN2 490/4885TSHR 4424/4885ALDH1A1 2245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.