SCHEMBL26528618

SCHEMBL26528618

Cc1cc(C)cc(-c2ccc3c(c2)c2cc(-c4cc(C)cc(C)c4)ccc2n3-c2ccccc2C(C)(C)C)c1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 1/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
RBP4 P02753 1/20 0.31
BRD9 Q9H8M2 1/20 0.31
BRD7 Q9NPI1 1/20 0.31
PTGES2 Q9H7Z7 2/20 0.30
PTGES O14684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26529172 0.99 SERPINE1 (0.32) SERPINE1RXRARXRBALDH1A1TSHR
SCHEMBL26528830 0.89 ICMT (0.37) SERPINE1RXRARXRBALDH1A1
SCHEMBL26529193 0.88 ICMT (0.37) SERPINE1RXRARXRBALDH1A1
SCHEMBL26528994 0.87 RXRB (0.37) SERPINE1RXRARXRBALDH1A1TSHR
SCHEMBL26529188 0.87 GRM2 (0.35) SERPINE1RXRARXRBRBP4PTGES2
SCHEMBL26529253 0.87 GRM2 (0.35) SERPINE1RXRARXRBRBP4PTGES2
SCHEMBL26529219 0.86 DHODH (0.36) SERPINE1ALDH1A1PTGES
SCHEMBL26529224 0.86 RXRB (0.36) SERPINE1RXRARXRBRBP4
SCHEMBL26529231 0.84 RBP4 (0.31) RBP4
SCHEMBL26529218 0.84 TRPA1 (0.37) RBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 SERPINE1 4578/4885RXRA 1633/4885RXRB 2498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.