SCHEMBL26528772

SCHEMBL26528772

Fc1cc(F)cc(-c2ccc3c(c2)c2cc(-c4cc(F)cc(F)c4)ccc2n3-c2ccccc2-c2ccc(-c3ccccc3-c3ccccc3)cc2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 3/20 0.35
SSTR2 P30874 1/20 0.35
MGLL Q99685 1/20 0.34
TDO2 P48775 1/20 0.33
IDO2 Q6ZQW0 1/20 0.33
ICMT O60725 1/20 0.33
NR3C1 P04150 1/20 0.33
METAP2 P50579 1/20 0.33
MAP4K4 O95819 1/20 0.33
HTR1A P08908 2/20 0.33
HTR2A P28223 1/20 0.33
HTR5A P47898 1/20 0.33
HTR6 P50406 1/20 0.33
GRM5 P41594 1/20 0.32
NT5E P21589 1/20 0.32
ALDH1A1 P00352 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
PGR P06401 1/20 0.32
HSD17B10 Q99714 1/20 0.31
NTRK1 P04629 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26528758 0.99 HTR7 (0.36) HTR7SSTR2MGLLTDO2IDO2
SCHEMBL26528767 0.96 NT5E (0.35) HTR7SSTR2MGLLTDO2IDO2
SCHEMBL26528762 0.96 SSTR2 (0.34) HTR7SSTR2MGLLTDO2IDO2
SCHEMBL26529010 0.93 MAP4K4 (0.35) HTR7SSTR2TDO2IDO2ICMT
SCHEMBL26529607 0.91 MAP4K4 (0.34) HTR7SSTR2TDO2IDO2MAP4K4
SCHEMBL26528785 0.89 NT5E (0.35) HTR7SSTR2TDO2IDO2ICMT
SCHEMBL26529289 0.88 MGLL (0.38) HTR7MGLLHTR1AHTR2AHTR5A
SCHEMBL26529255 0.86 MGLL (0.39) HTR7MGLLHTR1AHTR2AHTR5A
SCHEMBL26529291 0.86 MGLL (0.39) HTR7MGLLHTR1AHTR2AHTR5A
SCHEMBL21708990 0.86 MGLL (0.41) HTR7MGLLHTR1AHTR2AHTR5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 HTR7 3455/4885SSTR2 4874/4885MGLL 390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.