Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2645542 | 0.86 | GCK (0.33) | L3MBTL1 | |
| SCHEMBL2645256 | 0.86 | TSHR (0.33) | L3MBTL1 | |
| SCHEMBL2645512 | 0.83 | PIK3CD (0.34) | L3MBTL1 | |
| SCHEMBL4427570 | 0.66 | KDM4E (0.47) | — | |
| SCHEMBL8331366 | 0.65 | RXRA (0.40) | — | |
| SCHEMBL6831259 | 0.64 | ESR2 (0.42) | — | |
| SCHEMBL1878862 | 0.64 | HTR3A (0.42) | — | |
| SCHEMBL2646076 | 0.63 | CYP19A1 (0.41) | ALDH1A1 | |
| SCHEMBL20092549 | 0.63 | TYK2 (0.41) | L3MBTL1ALDH1A1 | |
| SCHEMBL779656 | 0.63 | ALDH1A1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169312-A2 | GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000058293-A2 | GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2000-10-05 | — | — | WO | disclosed |