SCHEMBL26529587

SCHEMBL26529587

Cc1cc(C)cc(-c2cc(-c3cc(C)cc(C(F)(F)F)c3)cc(-c3ccc4c(c3)c3cc(-c5cc(-c6cc(C)cc(C(F)(F)F)c6)cc(-c6cc(C(F)(F)F)cc(C(F)(F)F)c6)c5)ccc3n4-c3ccccc3-c3ccccc3F)c2)c1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 2/20 0.34
PDE10A Q9Y233 2/20 0.34
ICMT O60725 7/20 0.34
PTGES2 Q9H7Z7 1/20 0.34
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
GAA P10253 1/20 0.32
ATM Q13315 1/20 0.32
EPHX2 P34913 1/20 0.32
DHODH Q02127 1/20 0.32
GPBAR1 Q8TDU6 3/20 0.31
MAT2A P31153 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26529563 0.92 GAA (0.36) ICMTRXRARXRBGAAATM
SCHEMBL26540655 0.92 ICMT (0.38) PDE2APDE10AICMTPTGES2RXRA
SCHEMBL26529348 0.91 ICMT (0.36) ICMTRXRARXRB
SCHEMBL26529632 0.90 ICMT (0.36) ICMTRXRARXRB
SCHEMBL26529302 0.89 TRPA1 (0.36) ICMTRXRARXRBEPHX2GPBAR1
SCHEMBL26529483 0.89 ICMT (0.36) ICMTRXRARXRB
SCHEMBL26528853 0.89 ICMT (0.34) ICMTRXRARXRB
SCHEMBL26532469 0.89 ICMT (0.36) ICMTRXRARXRB
SCHEMBL26528984 0.89 ICMT (0.37) ICMTRXRARXRB
SCHEMBL26529615 0.88 ICMT (0.33) ICMTRXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 PDE2A 4081/4885PDE10A 4289/4885ICMT 36/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.