SCHEMBL26529563

SCHEMBL26529563

Cc1cc(C)cc(-c2cc(-c3cc(C)cc(C(F)(F)F)c3)cc(-c3ccc4c(c3)c3cc(-c5cc(-c6cc(C)cc(C(F)(F)F)c6)cc(-c6cc(C(F)(F)F)cc(C(F)(F)F)c6)c5)ccc3n4-c3ccccc3F)c2)c1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.36
ATM Q13315 1/20 0.36
ICMT O60725 9/20 0.36
RXRA P19793 2/20 0.35
RXRB P28702 2/20 0.35
ALDH1A1 P00352 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RXRG P48443 1/20 0.33
PIK3CA P42336 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26529587 0.92 PDE2A (0.34) GAAATMICMTRXRARXRB
SCHEMBL26540469 0.91 ICMT (0.41) GAAATMICMTRXRARXRB
SCHEMBL26529085 0.91 RXRA (0.38) ICMTRXRARXRBRXRG
SCHEMBL26529348 0.89 ICMT (0.36) ICMTRXRARXRBRXRG
SCHEMBL26529094 0.89 ALDH1A1 (0.36) ICMTRXRARXRBALDH1A1RXRG
SCHEMBL26529632 0.88 ICMT (0.36) ICMTRXRARXRBRXRG
SCHEMBL26529193 0.87 ICMT (0.37) ICMTRXRARXRBALDH1A1RXRG
SCHEMBL26528984 0.87 ICMT (0.37) ICMTRXRARXRBRXRG
SCHEMBL26528827 0.86 RXRA (0.37) ICMTRXRARXRBRXRG
SCHEMBL26529047 0.85 ICMT (0.40) ATMICMTRXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 GAA 1198/4885ATM 4086/4885ICMT 36/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.