SCHEMBL26529663

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30451809	0.94	DNMT1 (0.41)	DNMT1PRKD3MAP4K4FERCDK2
	SCHEMBL20707497	0.94	DNMT1 (0.41)	DNMT1PRKD3MAP4K4FERCDK2
	SCHEMBL1832121	0.90	DNMT1 (0.41)	DNMT1ALDH1A1DNM1IDO1TDO2
	SCHEMBL29976046	0.89	ATM (0.42)	DNMT1PRKD3MAP4K4FERCDK2
	SCHEMBL18918088	0.89	ATM (0.42)	DNMT1PRKD3MAP4K4FERCDK2
	SCHEMBL5807147	0.85	GABRA1 (0.38)	DNMT1ALDH1A1IDO1TDO2IDO2
	SCHEMBL24668214	0.85	MGLL (0.36)	ALDH1A1MEN1KMT2AATMTSPO
	SCHEMBL1832122	0.85	DNMT1 (0.38)	DNMT1PRKD3MAP4K4FERCDK2
	SCHEMBL25941989	0.84	KDM4E (0.41)	DNMT1PRKD3MAP4K4FERCDK2
	SCHEMBL24668239	0.83	MGLL (0.37)	ALDH1A1MAPK1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.