SCHEMBL5807147

SCHEMBL5807147

Cc1ccc2c(c1)c1cc(Br)ccc1n2-c1ccccc1-c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRA2 P47869 1/20 0.38
GABRB2 P47870 1/20 0.38
BCHE P06276 1/20 0.37
ACHE P22303 1/20 0.37
MAPT P10636 3/20 0.37
TP53 P04637 1/20 0.36
DNMT1 P26358 1/20 0.36
KMT2A Q03164 3/20 0.35
ALDH1A1 P00352 2/20 0.35
LMNA P02545 2/20 0.35
MEN1 O00255 2/20 0.35
KDM4E B2RXH2 1/20 0.35
RECQL P46063 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TDO2 P48775 2/20 0.35
IDO2 Q6ZQW0 2/20 0.35
IDO1 P14902 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28538774 0.91 BCHE (0.42) BCHEACHEMAPTTP53KMT2A
SCHEMBL30451809 0.91 DNMT1 (0.41) GABRA1GABRA5GABRA2GABRB2MAPT
SCHEMBL20707497 0.91 DNMT1 (0.41) GABRA1GABRA5GABRA2GABRB2MAPT
SCHEMBL29976046 0.87 ATM (0.42) GABRA1GABRA5GABRA2GABRB2DNMT1
SCHEMBL5812206 0.87 BCHE (0.43) BCHEACHEMAPTKMT2AALDH1A1
SCHEMBL18918088 0.87 ATM (0.42) GABRA1GABRA5GABRA2GABRB2DNMT1
SCHEMBL26529663 0.85 DNMT1 (0.39) GABRA1GABRA5GABRA2GABRB2MAPT
SCHEMBL25782608 0.82 ALDH1A1 (0.40) BCHEACHEMAPTTP53KMT2A
SCHEMBL26720863 0.82 L3MBTL1 (0.41) BCHEACHEMAPTKMT2AALDH1A1
SCHEMBL25941989 0.82 KDM4E (0.41) GABRA1GABRA5GABRA2GABRB2DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1780897-B Novel electroluminescent materials MERCK PATENT GMBH 2013-07-24 CN disclosed
CN-101495534-A Dicarbazole aromatic amine polymers and electronic devices SUMITOMO CHEMICAL CO (JP) 2009-07-29 CN disclosed
WO-2006096399-A2 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-14 WO disclosed
CN-1780897-A Novel electroluminescent materials COVION ORGANIC SEMICONDUCTORS (DE) 2006-05-31 CN disclosed