Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30587288 | 1.00 | KDM4E (0.30) | KDM4EMEN1ALDH1A1HPGDHTT | |
| SCHEMBL26114057 | 0.96 | — | — | |
| SCHEMBL30776456 | 0.91 | RORC (0.31) | ALDH1A1HPGDHTT | |
| SCHEMBL26535186 | 0.91 | RORC (0.31) | ALDH1A1HPGDHTT | |
| SCHEMBL30587224 | 0.89 | THRB (0.31) | MEN1ALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL26114998 | 0.89 | THRB (0.31) | MEN1ALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL30587198 | 0.89 | THRB (0.31) | MEN1ALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL31278508 | 0.89 | THRB (0.31) | MEN1ALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL26115041 | 0.89 | THRB (0.31) | MEN1ALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL27084115 | 0.87 | RORC (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183585-A1 | KRAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2023-09-28 | — | — | WO | disclosed |