Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30776456 | 1.00 | RORC (0.31) | RORCALDH1A1TP53GLAMAPT | |
| SCHEMBL27084115 | 0.96 | RORC (0.30) | RORC | |
| SCHEMBL26533737 | 0.91 | KDM4E (0.30) | ALDH1A1HPGDHTT | |
| SCHEMBL30587288 | 0.91 | KDM4E (0.30) | ALDH1A1HPGDHTT | |
| SCHEMBL26114057 | 0.87 | — | — | |
| SCHEMBL26536557 | 0.84 | KRAS (0.39) | — | |
| SCHEMBL30776339 | 0.83 | MTOR (0.31) | RORC | |
| SCHEMBL26535184 | 0.83 | MTOR (0.31) | RORC | |
| SCHEMBL27084089 | 0.83 | RORC (0.31) | RORC | |
| SCHEMBL31242606 | 0.81 | LMNA (0.31) | RORCALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183585-A1 | KRAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2023-09-28 | — | — | WO | disclosed |