⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26533904 | 0.83 | AURKA (0.31) | — | |
| SCHEMBL10457978 | 0.83 | PRMT6 (0.42) | — | |
| SCHEMBL26533895 | 0.77 | ACACB (0.33) | — | |
| SCHEMBL10459778 | 0.73 | PDE4A (0.42) | — | |
| SCHEMBL19880314 | 0.73 | PDE4A (0.42) | — | |
| SCHEMBL8923989 | 0.72 | PRMT6 (0.35) | — | |
| SCHEMBL10459678 | 0.72 | — | — | |
| SCHEMBL9964283 | 0.72 | — | — | |
| SCHEMBL25966452 | 0.71 | PRMT6 (0.42) | — | |
| SCHEMBL10457977 | 0.71 | PRMT6 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787833-B2 | Modified cyclic dinucleoside compounds as sting modulators | ALIGOS THERAPEUTICS, INC. (US) | 2023-10-17 | — | — | US | disclosed |