Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | MARS1 | P56192 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921787 | 0.84 | MARS1 (0.40) | PRMT6MARS1 | |
| SCHEMBL10457978 | 0.80 | PRMT6 (0.42) | PRMT6CYP1A2HTR1ACYP2D6ADRB3 | |
| SCHEMBL25966452 | 0.77 | PRMT6 (0.42) | PRMT6CYP1A2HTR1ACYP2D6ADRB3 | |
| SCHEMBL8922716 | 0.77 | PRMT6 (0.36) | PRMT6PDE4APDE4D | |
| SCHEMBL19509704 | 0.76 | PRMT6 (0.42) | PRMT6CYP1A2HTR1ACYP2D6ADRB3 | |
| SCHEMBL19500434 | 0.76 | PRMT6 (0.42) | PRMT6CYP1A2HTR1ACYP2D6ADRB3 | |
| SCHEMBL29772230 | 0.76 | PRMT6 (0.42) | PRMT6CYP1A2HTR1ACYP2D6ADRB3 | |
| SCHEMBL22984018 | 0.75 | PDE4A (0.47) | PDE4APDE4DP2RY12 | |
| SCHEMBL10459187 | 0.75 | PDE4A (0.47) | PDE4APDE4DP2RY12 | |
| SCHEMBL19509816 | 0.75 | PDE4A (0.47) | PDE4APDE4DP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703224-A | Antiviral c-nucleoside derivatives | NIPPON SHINYAKU CO. LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0733630-A1 | NUCLEOSIDE DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-09-25 | — | — | EP | disclosed |