SCHEMBL26533906

SCHEMBL26533906

O=C(Nc1ncnc2c([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)scc12)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA1 P30542 5/20 0.40
▸ ADORA3 P0DMS8 1/20 0.39
▸ ADORA2A P29274 1/20 0.39
▸ ADORA2B P29275 1/20 0.39
▸ CSF1R P07333 1/20 0.39
▸ LGALS9 O00182 1/20 0.39
▸ LGALS1 P09382 1/20 0.39
▸ LGALS3 P17931 1/20 0.39
▸ LGALS7; LGALS7B P47929 1/20 0.39
▸ SLC5A2 P31639 1/20 0.39
▸ HK1 P19367 1/20 0.39
▸ HK2 P52789 1/20 0.39
▸ LMNA P02545 2/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ GLA P06280 1/20 0.38
▸ PMP22 Q01453 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ NPY1R P25929 1/20 0.38
▸ HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26533894 0.84 GALR3 (0.44) ADORA1CSF1RLGALS9LGALS1LGALS3
SCHEMBL26533899 0.77 GALR3 (0.36) ADORA3CSF1RSMN1; SMN2NPC1HTT
SCHEMBL17479346 0.77 LGALS9 (0.38) ADORA1ADORA3ADORA2AADORA2BLGALS9
SCHEMBL17465396 0.77 LGALS9 (0.38) ADORA1ADORA3ADORA2AADORA2BLGALS9
SCHEMBL12261313 0.75 HIF1A (0.57) ADORA1ADORA3ADORA2AADORA2BLMNA
SCHEMBL23023836 0.72 ADK (0.72) ADORA3LMNAALDH1A1GLAPMP22
SCHEMBL24687181 0.72 ADK (0.72) ADORA3LMNAALDH1A1GLAPMP22
SCHEMBL24686959 0.72 ADK (0.51) ADORA1ADORA3ADORA2AADORA2BLMNA
SCHEMBL31123791 0.72 ADK (0.72) ADORA3LMNAALDH1A1GLAPMP22
SCHEMBL26533904 0.72 AURKA (0.31) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11787833-B2 Modified cyclic dinucleoside compounds as sting modulators ALIGOS THERAPEUTICS, INC. (US) 2023-10-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11787833-B2 Modified cyclic dinucleoside compounds as sting modulators STING1, CGAS, IRF3 ADORA1 295/4885ADORA3 378/4885ADORA2A 299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback