SCHEMBL26535461

SCHEMBL26535461

N#Cc1ccc(-c2cc(-c3ccc(C#N)cc3)cc(-c3ccc4c(c3)c3cc(-c5cc(-c6ccc(C#N)cc6)cc(-c6ccc(C#N)cc6)c5)ccc3n4-c3ccccc3C(F)(F)F)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.48
PDK2 Q15119 1/20 0.38
AR P10275 4/20 0.37
SLC22A12 Q96S37 1/20 0.36
PTPN5 P54829 2/20 0.35
PDPK1 O15530 1/20 0.35
TRPV4 Q9HBA0 1/20 0.35
PGR P06401 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
SYK P43405 1/20 0.34
MAP4K4 O95819 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26535464 0.93 KIF11 (0.39) KIF11PDK2ARSLC22A12PTPN5
SCHEMBL21116555 0.87 KIF11 (0.56) KIF11PDK2ARPTPN5TRPV4
SCHEMBL26529084 0.87 LDHA (0.40) KIF11KDM4EMAPT
SCHEMBL26529170 0.87 LDHA (0.40) KIF11KDM4EMAPT
SCHEMBL26529151 0.87 LDHA (0.40) KIF11KDM4EMAPT
SCHEMBL26535467 0.86 AR (0.45) ARPGR
SCHEMBL21116551 0.86 KIF11 (0.50) KIF11PDK2ARPTPN5PDPK1
SCHEMBL17950235 0.85 KIF11 (0.45) KIF11PDK2ARPTPN5TRPV4
SCHEMBL26535347 0.84 AR (0.46) ARPTPN5PGR
SCHEMBL26534937 0.84 KIF11 (0.42) KIF11KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 KIF11 3651/4885PDK2 2410/4885AR 3385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.