SCHEMBL26535467

SCHEMBL26535467

N#Cc1ccc(-c2cc(-c3ccc(C#N)c(C#N)c3)cc(-c3ccc4c(c3)c3cc(-c5cc(-c6ccc(C#N)c(C#N)c6)cc(-c6ccc(C#N)c(C#N)c6)c5)ccc3n4-c3ccccc3C(F)(F)F)c2)cc1C#N

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AR P10275 16/20 0.45
PGR P06401 4/20 0.40
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
RXRG P48443 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26535347 0.88 AR (0.46) ARPGR
SCHEMBL26535464 0.86 KIF11 (0.39) ARPGRRXRARXRG
SCHEMBL26535461 0.86 KIF11 (0.48) ARPGR
SCHEMBL26540108 0.83 AR (0.52) ARPGR
SCHEMBL26529084 0.83 LDHA (0.40)
SCHEMBL26529151 0.83 LDHA (0.40)
SCHEMBL26529170 0.83 LDHA (0.40)
SCHEMBL26534941 0.81 ICMT (0.40) RXRARXRBRXRG
SCHEMBL26534939 0.81 MAPT (0.37)
SCHEMBL26534933 0.81 TRPA1 (0.44) ARPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 AR 3385/4885PGR 3828/4885RXRA 1633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.