Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25834064 | 0.84 | NOTUM (0.46) | CES2NOTUMRXRARXRBRXRG | |
| SCHEMBL14893085 | 0.83 | CES2 (0.64) | CES2NOTUMGAARXRARXRB | |
| SCHEMBL17760574 | 0.81 | CES2 (0.65) | CES2P2RX1MAPTNPSR1 | |
| SCHEMBL12429619 | 0.81 | CES2 (0.61) | CES2NOTUMGAARXRARXRB | |
| SCHEMBL1999038 | 0.79 | NOTUM (0.77) | CES2NOTUMGAAP2RX1HDAC3 | |
| SCHEMBL27902497 | 0.79 | CES2 (0.59) | CES2MAPTCES1 | |
| SCHEMBL29459924 | 0.78 | CES2 (0.57) | CES2NOTUMGAARXRARXRB | |
| SCHEMBL20869052 | 0.78 | CES2 (0.57) | CES2NOTUMGAARXRARXRB | |
| SCHEMBL19280563 | 0.78 | CES2 (0.57) | CES2NOTUMGAARXRARXRB | |
| SCHEMBL19541391 | 0.76 | NOTUM (0.62) | CES2NOTUMGAARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373941-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-11-23 | — | — | US | disclosed |
| US-20230138100-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230373941-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP2E1, GPX1, ERCC1 | CES2 38/4885NOTUM 2662/4885GAA 3173/4885 |
| US-20230138100-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP2C19, ETV6, ESR1 | CES2 92/4885NOTUM 1884/4885GAA 3076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.