Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26536749 | 0.84 | CES2 (0.59) | NOTUMCES2RXRARXRBRXRG | |
| SCHEMBL14107748 | 0.79 | NOTUM (0.46) | NOTUMCES2PRKCAPRKCDMRGPRX4 | |
| SCHEMBL16716029 | 0.79 | PTPN1 (0.54) | NOTUMCES2PRKCAPRKCDMRGPRX4 | |
| SCHEMBL13099993 | 0.78 | RXRA (0.52) | NOTUMCES2PRKCAPRKCDMRGPRX4 | |
| SCHEMBL13679018 | 0.78 | CES2 (0.47) | CES2MRGPRX4IDO1MLYCD | |
| SCHEMBL15746568 | 0.75 | CES2 (0.44) | NOTUMCES2PRKCAPRKCDMRGPRX4 | |
| SCHEMBL13528943 | 0.74 | KMT2A (0.45) | PRKCAPRKCDLMNA | |
| SCHEMBL21712070 | 0.73 | NOTUM (0.65) | NOTUMCES2PRKCAPRKCDMRGPRX4 | |
| SCHEMBL13611312 | 0.73 | MASP2 (0.40) | NOTUMPRKCAPRKCDMRGPRX4LMNA | |
| SCHEMBL5776968 | 0.72 | IDO1 (0.54) | CES2IDO1MLYCDRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230225196-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230225196-A1 | MATERIALS FOR ELECTRONIC DEVICES | SELE, EPHA6, EPX | NOTUM 2686/4885CES2 37/4885PRKCA 3215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.