SCHEMBL26538504

SCHEMBL26538504

FC(F)(F)c1cc(-c2ccccc2-n2c3ccc(-c4cc(-c5ccc(C(F)(F)F)cc5C(F)(F)F)cc(-c5ccc(C(F)(F)F)cc5C(F)(F)F)c4)cc3c3cc(-c4cc(-c5ccc(C(F)(F)F)cc5C(F)(F)F)cc(-c5ccc(C(F)(F)F)cc5C(F)(F)F)c4)ccc32)cc(C(F)(F)F)c1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 1/20 0.36
EDNRA P25101 1/20 0.36
ALOX5AP P20292 1/20 0.35
FEN1 P39748 1/20 0.35
ICMT O60725 8/20 0.35
TRPA1 O75762 2/20 0.33
CYP2C9 P11712 1/20 0.33
SCN9A Q15858 1/20 0.33
GPR3 P46089 1/20 0.32
EPHX2 P34913 1/20 0.31
KIF11 P52732 1/20 0.31
NR3C1 P04150 1/20 0.31
PGR P06401 1/20 0.31
HSP90AA1 P07900 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26538501 0.92 TRPA1 (0.40) ALOX5APFEN1ICMTTRPA1SCN9A
SCHEMBL26538526 0.91 ICMT (0.40) ICMTKIF11
SCHEMBL26529341 0.90 ICMT (0.32) EDNRBEDNRAICMTTRPA1CYP2C9
SCHEMBL26538507 0.89 KIF11 (0.39) ICMTKIF11
SCHEMBL26533963 0.89 ICMT (0.41) ICMTKIF11
SCHEMBL26539889 0.87 ICMT (0.40) ICMTKIF11
SCHEMBL26529328 0.87 ICMT (0.40) ICMTKIF11
SCHEMBL26529371 0.86 ICMT (0.43) ICMTKIF11
SCHEMBL26529374 0.86 ICMT (0.40) ICMTKIF11
SCHEMBL26537554 0.86 ICMT (0.41) ICMTKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 EDNRB 4799/4885EDNRA 4532/4885ALOX5AP 1167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.