SCHEMBL26540299

SCHEMBL26540299

N#Cc1cc(C#N)cc(-c2ccccc2-n2c3ccc(-c4cc(-c5cc(C(F)(F)F)cc(C(F)(F)F)c5)cc(-c5cc(C(F)(F)F)cc(C(F)(F)F)c5)c4)cc3c3cc(-c4cc(-c5cc(C(F)(F)F)cc(C(F)(F)F)c5)cc(-c5cc(C(F)(F)F)cc(C(F)(F)F)c5)c4)ccc32)c1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.41
RXRG P48443 1/20 0.41
ICMT O60725 6/20 0.35
KIF11 P52732 1/20 0.34
PDK2 Q15119 2/20 0.34
PTPN5 P54829 1/20 0.33
XDH P47989 1/20 0.33
PGR P06401 1/20 0.33
TAS2R14 Q9NYV8 1/20 0.33
TACR1 P25103 2/20 0.32
AR P10275 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26538974 1.00 RXRA (0.41) RXRARXRGICMTKIF11PDK2
SCHEMBL26529545 0.93 RXRA (0.37) RXRARXRGICMTPDK2XDH
SCHEMBL26539720 0.90 KIF11 (0.35) RXRARXRGKIF11PDK2PGR
SCHEMBL26529548 0.90 KIF11 (0.35) RXRARXRGKIF11PDK2PGR
SCHEMBL26538526 0.89 ICMT (0.40) RXRARXRGICMTKIF11TACR1
SCHEMBL26538970 0.89 PTPN5 (0.39) ICMTPTPN5PGRAR
SCHEMBL26540297 0.89 AR (0.44) RXRARXRGKIF11PDK2PGR
SCHEMBL26533963 0.88 ICMT (0.41) RXRARXRGICMTKIF11TACR1
SCHEMBL20849509 0.86 RXRA (0.36) RXRARXRGICMTKIF11PDK2
SCHEMBL21414162 0.86 RXRA (0.44) RXRARXRGICMTKIF11PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 RXRA 1633/4885RXRG 1935/4885ICMT 36/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.