Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 14/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 13/20 | 0.40 |
| ▸ | GSK3B | P49841 | 5/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | GRN | P28799 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22286724 | 0.82 | KDM4E (0.49) | CDK2CCNE1GSK3BCDK1CDK4 | |
| SCHEMBL26540428 | 0.81 | CDK2 (0.39) | CDK2CCNE1GSK3BCDK1CDK4 | |
| SCHEMBL25292491 | 0.81 | SMYD3 (0.38) | CDK2CCNE1GSK3BCDK1CDK4 | |
| SCHEMBL22286911 | 0.81 | CA12 (0.42) | CDK2CCNE1GSK3BCDK1CDK4 | |
| Lithium Ion SCHEMBL22286872 | 0.79 | CDK2 (0.37) | CDK2CCNE1GSK3BCDK1CDK4 | |
| SCHEMBL24589254 | 0.78 | NAMPT (0.44) | CDK2CCNE1GSK3BCDK1CDK4 | |
| SCHEMBL7703155 | 0.77 | LMNA (0.47) | CDK2CCNE1GSK3BCDK1CDK4 | |
| SCHEMBL26540840 | 0.76 | CCNE1 (0.35) | CDK2CCNE1GSK3BKDM4EKCNT1 | |
| SCHEMBL25941741 | 0.74 | CDK2 (0.52) | CDK2CCNE1GSK3BCDK1CDK4 | |
| SCHEMBL8014330 | 0.73 | SMN1; SMN2 (0.43) | KDM4EGRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072096-A1 | TETRAHYDROFURAN-CONTAINING POLYCYCLIC DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 优领医药科技(香港)有限公司 | 2023-05-04 | — | — | WO | disclosed |