SCHEMBL26543208

SCHEMBL26543208

c1ccc2c(c1)oc1c2ccc2sc3c4c5ccccc5c5ccccc5c4c4ccccc4c3c21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR2 Q92731 3/20 0.37
▸ ESR1 P03372 1/20 0.37
▸ ALOX5 P09917 3/20 0.37
▸ AHR P35869 2/20 0.35
▸ JAK2 O60674 1/20 0.34
▸ ZAP70 P43403 1/20 0.34
▸ SYK P43405 1/20 0.34
▸ KDM4E B2RXH2 4/20 0.33
▸ MAPT P10636 3/20 0.33
▸ HPGD P15428 3/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ CYP3A4 P08684 2/20 0.33
▸ CASP7 P55210 2/20 0.33
▸ HSD17B10 Q99714 2/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ ALPI P09923 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ PKM P14618 1/20 0.33
▸ CASP3 P42574 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16919484 0.87 ALOX5 (0.42) ESR2ESR1ALOX5AHRJAK2
SCHEMBL16919467 0.82 ESR2 (0.41) ESR2ESR1ALOX5AHRJAK2
SCHEMBL16919549 0.79 MAPT (0.39) ALOX5AHRJAK2ZAP70SYK
SCHEMBL14476381 0.79 AHR (0.46) ALOX5AHRJAK2ZAP70SYK
SCHEMBL24039790 0.79 AHR (0.46) ALOX5AHRJAK2ZAP70SYK
SCHEMBL31668235 0.79 AHR (0.46) ALOX5AHRJAK2ZAP70SYK
SCHEMBL1637446 0.79 GPR3 (0.43) ESR2ESR1ALOX5AHRJAK2
SCHEMBL22011700 0.78 ESR2 (0.40) ESR2ESR1KDM4EMAPTHPGD
SCHEMBL31282478 0.76 AHR (0.43) ESR2ESR1ALOX5AHRJAK2
SCHEMBL23242811 0.75 MAPT (0.50) ALOX5AHRKDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230134350-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2023-05-04 — — US disclosed
US-20230134350-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2023-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230134350-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME OR10J3, ODC1, OTC ESR2 1426/4885ESR1 762/4885ALOX5 1030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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