SCHEMBL1637446

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16919484	0.91	ALOX5 (0.42)	GPR3ESR2ESR1ALOX5MAPT
	SCHEMBL16919467	0.86	ESR2 (0.41)	GPR3ESR2ESR1ALOX5MAPT
	SCHEMBL25279286	0.85	AHR (0.53)	ESR2ESR1ALOX5MAPTMEN1
	SCHEMBL25276101	0.85	AHR (0.53)	ALOX5MAPTMEN1KMT2APOLB
	SCHEMBL17431206	0.85	ALOX5 (0.40)	GPR3ESR2ESR1ALOX5MAPT
	SCHEMBL16919549	0.83	MAPT (0.39)	ALOX5MAPTMEN1KMT2ABLM
	SCHEMBL22057685	0.83	MEN1 (0.35)	ESR2ESR1ALOX5MAPTMEN1
	SCHEMBL31282478	0.83	AHR (0.43)	GPR3ESR2ESR1ALOX5MEN1
	SCHEMBL20821581	0.82	ALOX5 (0.50)	GPR3ESR2ESR1ALOX5AHR
	SCHEMBL22011700	0.82	ESR2 (0.40)	GPR3ESR2ESR1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.