Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ATP4A | P20648 | 1/20 | 0.33 |
| ▸ | ATP4B | P51164 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 7/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21091002 | 0.80 | TYK2 (0.39) | ATP4AATP4BFYNTYK2JAK1 | |
| SCHEMBL24497533 | 0.79 | TYK2 (0.33) | DHFRABCB1ABCC1FYNTYK2 | |
| SCHEMBL26545645 | 0.78 | TPMT (0.33) | ABCB1ABCC1FYNTYK2JAK1 | |
| SCHEMBL24899717 | 0.78 | FYN (0.40) | FYNTYK2JAK1CYP2C19 | |
| SCHEMBL21547599 | 0.77 | PTGS2 (0.46) | DHFRPTGS2HTR2A | |
| SCHEMBL26511743 | 0.75 | P2RX3 (0.32) | FYNTYK2JAK1CYP2C19P2RX3 | |
| SCHEMBL26118652 | 0.75 | TPMT (0.40) | ABCB1ABCC1JAK2 | |
| SCHEMBL26514504 | 0.74 | ATP4A (0.30) | ATP4AATP4B | |
| SCHEMBL9886154 | 0.72 | PTGS2 (0.42) | PTGS2HTR2A | |
| SCHEMBL29020402 | 0.72 | TYK2 (0.38) | ABCB1ABCC1TYK2HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4257587-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shenzhen Chipscreen Biosciences Co., Ltd. (CN) | 2023-10-11 | — | — | EP | disclosed |