SCHEMBL26545606

SCHEMBL26545606

COCCOCCOCCOCCOc1cc(C(=O)O)cc(OCCOCCOCCOCCOC)c1OCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
LMNA P02545 1/20 0.48
HPGD P15428 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
KDM4E B2RXH2 1/20 0.46
SMPD1 P17405 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.46
RXRA P19793 1/20 0.46
SLC6A5 Q9Y345 3/20 0.45
NR4A2 P43354 2/20 0.45
NR4A1 P22736 1/20 0.44
NR4A3 Q92570 1/20 0.44
ALDH1A1 P00352 1/20 0.44
PTK2B Q14289 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30036849 0.94 KMT2A (0.46) KMT2AMEN1LMNAHPGDSMN1; SMN2
SCHEMBL30036048 0.94 KMT2A (0.46) KMT2AMEN1LMNAHPGDSMN1; SMN2
SCHEMBL30037023 0.94 KMT2A (0.46) KMT2AMEN1LMNAHPGDSMN1; SMN2
SCHEMBL26545590 0.90 LMNA (0.62) KMT2AMEN1LMNAHPGDSMN1; SMN2
SCHEMBL31007004 0.87 KMT2A (0.51) KMT2AMEN1LMNASMN1; SMN2KDM4E
SCHEMBL26545271 0.86 TNFRSF1A (0.47) KMT2AMEN1ALDH1A1PTK2B
SCHEMBL8207625 0.86 TNFRSF1A (0.47) KMT2AMEN1ALDH1A1PTK2B
SCHEMBL13498580 0.86 TNFRSF1A (0.47) KMT2AMEN1ALDH1A1PTK2B
SCHEMBL793724 0.83 MEN1 (0.65) KMT2AMEN1LMNAHPGDSMN1; SMN2
SCHEMBL30036356 0.83 RAB9A (0.50) KMT2AMEN1LMNASMN1; SMN2MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023198813-A1 DENDRITIC MOLECULES, PROCESS FOR THEIR PREPARATION AND USES THEREOF SUPERBRANCHE (FR) 2023-10-19 WO disclosed
WO-2023198812-A1 COMPOSITIONS OF DISPERSED SYSTEMS FOR BIOMEDICAL APPLICATIONS, PROCESS FOR THEIR PREPARATION AND USES THEREOF SUPERBRANCHE (FR) 2023-10-19 WO disclosed
EP-4260876-A1 COMPOSITIONS OF DISPERSED SYSTEMS FOR BIOMEDICAL APPLICATIONS, PROCESS FOR THEIR PREPARATION AND USES THEREOF Superbranche (FR) 2023-10-18 EP disclosed
EP-4261244-A1 DENDRITIC MOLECULES, PROCESS FOR THEIR PREPARATION AND USES THEREOF Superbranche (FR) 2023-10-18 EP disclosed