SCHEMBL8207625

SCHEMBL8207625

COCCOCCOCCOc1cc(C(=O)O)cc(OCCOCCOCCOC)c1OCCOCCOCCOC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNFRSF1A P19438 1/20 0.47
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA3 P07451 1/20 0.43
PKM P14618 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
TPMT P51580 1/20 0.42
ALDH1A1 P00352 1/20 0.42
PTK2B Q14289 1/20 0.42
PTGS2 P35354 1/20 0.41
POLB P06746 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13498580 1.00 TNFRSF1A (0.47) TNFRSF1AKMT2AMEN1CA12CA1
SCHEMBL26545271 1.00 TNFRSF1A (0.47) TNFRSF1AKMT2AMEN1CA12CA1
SCHEMBL30036849 0.88 KMT2A (0.46) KMT2AMEN1ALDH1A1PTK2BPOLB
SCHEMBL30036048 0.88 KMT2A (0.46) KMT2AMEN1ALDH1A1PTK2BPOLB
SCHEMBL30037023 0.88 KMT2A (0.46) KMT2AMEN1ALDH1A1PTK2BPOLB
SCHEMBL16072742 0.87 RARB (0.46) KMT2AMEN1CA12CA1CA2
SCHEMBL16333870 0.87 TNFRSF1A (0.47) TNFRSF1AKMT2AMEN1ALDH1A1PTK2B
SCHEMBL26545606 0.86 KMT2A (0.50) KMT2AMEN1ALDH1A1PTK2B
SCHEMBL23558403 0.86 TNFRSF1A (0.46) TNFRSF1AKMT2AMEN1ALDH1A1PTK2B
SCHEMBL797245 0.86 KMT2A (0.48) TNFRSF1AKMT2AMEN1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12540278-B2 Temperature programmable small molecules for thermoresponsive smart windows and applications thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2026-02-03 US disclosed
US-20240400898-A1 TEMPERATURE PROGRAMMABLE SMALL MOLECULES FOR THERMORESPONSIVE SMART WINDOWS AND APPLICATIONS THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2024-12-05 US disclosed
EP-4347550-A1 ONE-COMPONENT DELIVERY SYSTEM FOR NUCLEIC ACIDS The Trustees of the University of Pennsylvania (US) 2024-04-10 EP disclosed
WO-2022251191-A1 ONE-COMPONENT DELIVERY SYSTEM FOR NUCLEIC ACIDS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2022-12-01 WO disclosed
US-9623046-B2 Amphiphilic Janus-dendrimers THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2017-04-18 US disclosed
US-8404216-B2 Dendritic chelated compounds, methods for making the same and pharmaceutical compositions containing the same CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2013-03-26 US disclosed
US-8404216-B2 Dendritic chelated compounds, methods for making the same and pharmaceutical compositions containing the same CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2013-03-26 US disclosed
US-20120308640-A1 AMPHIPHILIC JANUS-DENDRIMERS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2012-12-06 US disclosed
US-20110021626-A1 ENCAPSULATION OF VITAMIN C INTO WATER SOLUBLE DENDRIMERS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) 2011-01-27 US disclosed
US-20110021626-A1 ENCAPSULATION OF VITAMIN C INTO WATER SOLUBLE DENDRIMERS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) 2011-01-27 US disclosed
US-20100104512-A1 Dendritic Chelated Compounds, Methods for Making the Same and Pharmaceutical Compositions Containing the Same CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-04-29 US disclosed
US-20100104512-A1 Dendritic Chelated Compounds, Methods for Making the Same and Pharmaceutical Compositions Containing the Same CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-04-29 US disclosed
WO-2008043911-A2 DENDRITIC CHELATED COMPOUNDS, METHODS FOR MAKING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2008-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120308640-A1 AMPHIPHILIC JANUS-DENDRIMERS OR10J3, H1-10, CXCR3 TNFRSF1A 2551/4885KMT2A 2299/4885MEN1 755/4885
US-20110021626-A1 ENCAPSULATION OF VITAMIN C INTO WATER SOLUBLE DENDRIMERS PROC, CD44, CCNC TNFRSF1A 2718/4885KMT2A 3398/4885MEN1 1722/4885
US-12540278-B2 Temperature programmable small molecules for thermoresponsive smart windows and applications thereof CRY1, C1S, CRY2 TNFRSF1A 369/4885KMT2A 715/4885MEN1 2168/4885
US-20100104512-A1 Dendritic Chelated Compounds, Methods for Making the Same and Pharmaceutical Compositions Containing the Same ZYX, CXCR4, ZFX TNFRSF1A 2213/4885KMT2A 3370/4885MEN1 398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.