Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 3/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | STAMBP | O95630 | 1/20 | 0.38 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10857049 | 0.83 | EPHX2 (0.46) | EPHX2FFAR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL17186398 | 0.80 | EPHX2 (0.49) | EPHX2FFAR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3262436 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL17186463 | 0.79 | EPHX2 (0.48) | EPHX2FFAR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3070030 | 0.78 | — | — | |
| SCHEMBL1259566 | 0.76 | — | — | |
| SCHEMBL18072257 | 0.76 | — | — | |
| SCHEMBL21743428 | 0.76 | KDM4E (0.45) | EPHX2FFAR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL18964090 | 0.76 | KDM4E (0.46) | EPHX2FFAR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL13024156 | 0.76 | FFAR2 (0.58) | EPHX2FFAR2CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024102752-A1 | SMALL MOLECULE MODULATORS OF PAR2 AND USES THEREOF | PARMEDICS, INC. (US) | 2024-05-16 | — | — | WO | disclosed |
| WO-2023187670-A1 | DIAZABICYCLOOCTANE DERIVATIVES USEFUL AS MATRIX METALLOPROTEINASE INHIBITORS | VASA THERAPEUTICS SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (PL) | 2023-10-05 | — | — | WO | disclosed |