Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | STAMBP | O95630 | 1/20 | 0.34 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26546183 | 0.83 | EPHX2 (0.53) | EPHX2FFAR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL10854597 | 0.73 | HTT (0.44) | EPHX2FFAR2 | |
| SCHEMBL29128627 | 0.73 | EPHX2 (0.47) | EPHX2FFAR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL17186398 | 0.72 | EPHX2 (0.49) | EPHX2FFAR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3262436 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL17186463 | 0.71 | EPHX2 (0.48) | EPHX2FFAR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3070030 | 0.70 | — | — | |
| SCHEMBL10856446 | 0.70 | KDM4C (0.43) | — | |
| SCHEMBL10854078 | 0.70 | NPC1 (0.30) | — | |
| SCHEMBL10857203 | 0.69 | MDM2 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4565826-A | HYPOTENSIVE, CARDIONASCULAR, ANTIULCER, ANTISECRETORY, GASTROINTESTINAL DISORDERS | WILLIAM H. RORER, INC. (US) | 1986-01-21 | — | — | US | disclosed |
| US-4436911-A | HYPOTENSIVE, ANTISPASMODIC, ANTIULCER, ANTIPARASITIC | WILLIAM H. RORER, INC. (US) | 1984-03-13 | — | — | US | disclosed |