Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MELK | Q14680 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DBH | P09172 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10060476 | 0.80 | CES2 (0.41) | GAAPKMALDH1A1HPGDTAS1R3 | |
| SCHEMBL25698096 | 0.79 | TSHR (0.33) | GAAHSD17B10PKMALOX15ALDH1A1 | |
| SCHEMBL17050413 | 0.72 | GSK3B (0.52) | GAAALDH1A1HPGDL3MBTL1HDAC3 | |
| SCHEMBL10161072 | 0.72 | DAO (0.54) | GAAPKMALDH1A1HPGDHDAC3 | |
| SCHEMBL12744773 | 0.72 | DAO (0.59) | HSD17B10ALDH1A1HPGDMELKTDP1 | |
| SCHEMBL10161070 | 0.72 | NPSR1 (0.53) | ALDH1A1HPGDTDP1L3MBTL1HDAC3 | |
| SCHEMBL19176675 | 0.71 | DAO (0.57) | GAAALDH1A1HPGDTAS1R3TAS1R1 | |
| SCHEMBL3195402 | 0.71 | CES2 (0.65) | GAAALDH1A1HPGDMELKL3MBTL1 | |
| SCHEMBL13423078 | 0.71 | F2 (0.57) | GAAALDH1A1HPGDMELKKDM4E | |
| SCHEMBL12667404 | 0.69 | HCAR3 (0.37) | ALOX15L3MBTL1CCNA2CDK2HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023219939-A1 | COMPOUNDS AND METHODS FOR TREATING FRIEDREICH'S ATAXIA | Design Therapeutics, Inc. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023192642-A2 | METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE | Design Therapeutics, Inc. (US) | 2023-10-05 | — | — | WO | disclosed |