Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8142798 | 0.69 | CDK2 (0.42) | CDK2CCNA2MAPTALDH1A1HSD17B10 | |
| SCHEMBL23682669 | 0.69 | GFER (0.36) | CDK2CCNA2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14099757 | 0.68 | L3MBTL1 (0.44) | CDK2CCNA2MAPTSMN1; SMN2LMNA | |
| SCHEMBL1841799 | 0.67 | L3MBTL1 (0.46) | MAPTALDH1A1HSD17B10ALOX15CYP1A2 | |
| SCHEMBL23815725 | 0.66 | SHMT2 (0.39) | CDK2CCNA2MAPTALDH1A1CDK5 | |
| SCHEMBL2880579 | 0.66 | COPS5 (0.35) | — | |
| SCHEMBL23815751 | 0.65 | GFER (0.36) | CDK2CCNA2ALDH1A1LMNAGAA | |
| SCHEMBL17248050 | 0.64 | MAPK14 (0.50) | CDK2ALDH1A1CDK5KDM4ESMN1; SMN2 | |
| SCHEMBL8145446 | 0.64 | GAA (0.63) | MAPTALDH1A1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL2878486 | 0.63 | TNIK (0.49) | CDK2CCNA2MAPTALDH1A1CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244682-A1 | METHODS AND COMPOUNDS FOR MODULATING INHERITED GENETIC DISEASES | Design Therapeutics, Inc. (US) | 2023-12-21 | — | — | WO | disclosed |
| WO-2023192642-A2 | METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE | Design Therapeutics, Inc. (US) | 2023-10-05 | — | — | WO | disclosed |