Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430963 | 0.96 | LMNA (0.46) | LMNATSHRNFKB1PMP22CYP2D6 | |
| SCHEMBL21696279 | 0.92 | LMNA (0.40) | LMNATSHRNFKB1PMP22CYP2D6 | |
| SCHEMBL26547300 | 0.91 | LMNA (0.50) | LMNATSHRNFKB1PMP22CYP2D6 | |
| SCHEMBL13512958 | 0.85 | LMNA (0.39) | LMNATSHRNFKB1PMP22CYP2D6 | |
| SCHEMBL1067916 | 0.83 | LMNA (0.42) | LMNATSHRNFKB1CYP2D6KMT2A | |
| Hydrochloric Acid SCHEMBL2654446 | 0.81 | LMNA (0.41) | LMNATSHRKMT2AALDH1A1BLM | |
| Water SCHEMBL2651084 | 0.81 | LMNA (0.41) | LMNATSHRKMT2AALDH1A1BLM | |
| Sebacic Acid SCHEMBL28847911 | 0.78 | TSHR (0.55) | LMNATSHRNFKB1PMP22CYP2D6 | |
| SCHEMBL28207119 | 0.77 | TSHR (0.48) | LMNATSHRKMT2AALDH1A1RECQL | |
| Sebacic Acid SCHEMBL28847912 | 0.77 | TSHR (0.52) | LMNATSHRNFKB1PMP22CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331685-A1 | HERBICIDAL COMPOUNDS AND METHODS OF USE THEREOF | AG PLENUS LTD (IL) | 2023-10-19 | — | — | US | disclosed |
| US-20230331685-A1 | HERBICIDAL COMPOUNDS AND METHODS OF USE THEREOF | AG PLENUS LTD (IL) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331685-A1 | HERBICIDAL COMPOUNDS AND METHODS OF USE THEREOF | DDT, HDHD5, HPD | LMNA 3899/4885TSHR 3503/4885NFKB1 4515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.