SCHEMBL26548161

SCHEMBL26548161

Fc1ccc(-c2ccc3cc(-c4ccc(-c5cc(C(F)(F)F)cc(C(F)(F)F)c5)cc4)ccc3c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 6/20 0.49
RXRB P28702 6/20 0.49
RXRG P48443 5/20 0.49
PGR P06401 4/20 0.43
NR3C1 P04150 1/20 0.43
TDP1 Q9NUW8 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.38
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
NFKB1 P19838 1/20 0.38
CYP2C19 P33261 1/20 0.38
RECQL P46063 1/20 0.38
RAB9A P51151 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26548516 1.00 RXRA (0.49) RXRARXRBRXRGPGRNR3C1
SCHEMBL26548138 1.00 RXRA (0.49) RXRARXRBRXRGPGRNR3C1
SCHEMBL26548141 0.98 RXRA (0.47) RXRARXRBRXRGPGRNR3C1
SCHEMBL26548660 0.94 RXRA (0.47) RXRARXRBRXRGPGRNR3C1
SCHEMBL26549004 0.94 RXRA (0.47) RXRARXRBRXRGPGRNR3C1
SCHEMBL26548681 0.94 RXRA (0.47) RXRARXRBRXRGPGRNR3C1
SCHEMBL26548661 0.93 RXRA (0.46) RXRARXRBRXRGPGRNR3C1
SCHEMBL26548168 0.92 RXRA (0.55) RXRARXRBRXRGPGRESR1
SCHEMBL26549932 0.92 RXRA (0.55) RXRARXRBRXRGPGRESR1
SCHEMBL19331992 0.90 RXRA (0.57) RXRARXRBRXRGTDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 RXRA 4514/4885RXRB 4516/4885RXRG 4629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.