SCHEMBL26548776

SCHEMBL26548776

C[Si](C)(C)c1ccc(-c2ccc3ccc(-c4ccc(-c5cccc6c5oc5ccccc56)nc4)cc3c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.42
PRKDC P78527 7/20 0.33
PIK3CD O00329 1/20 0.33
PIK3CB P42338 1/20 0.33
GGPS1 O95749 1/20 0.33
GRK5 P34947 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
NPC1 O15118 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
RAB9A P51151 1/20 0.32
JAK2 O60674 1/20 0.31
JAK1 P23458 1/20 0.31
TYK2 P29597 1/20 0.31
JAK3 P52333 1/20 0.31
PTGES2 Q9H7Z7 1/20 0.31
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26548255 0.97 ALOX5 (0.43) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL17212576 0.92 ALOX5 (0.48) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL26549272 0.92 ALOX5 (0.39) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL17212568 0.89 ALOX5 (0.49) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL26555137 0.88 ALOX5 (0.43) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL26555157 0.88 ALOX5 (0.43) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL26548766 0.88 ALOX5 (0.43) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL26548944 0.87 ALOX5 (0.51) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL26548620 0.87 ALOX5 (0.51) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL26555166 0.87 ALOX5 (0.40) ALOX5PRKDCPIK3CDPIK3CBGGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 ALOX5 1577/4885PRKDC 2422/4885PIK3CD 4765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.