SCHEMBL26548901

SCHEMBL26548901

FC(F)(F)c1cc(-c2ccc(-c3ccc4ccc(-c5ccc(-c6cccnc6)cc5)cc4c3)cc2)cc(C(F)(F)F)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 7/20 0.59
CYP11B1 P15538 6/20 0.59
CYP17A1 P05093 4/20 0.59
CYP19A1 P11511 4/20 0.59
KDR P35968 3/20 0.55
DGAT1 O75907 1/20 0.52
KCNH2 Q12809 1/20 0.52
FGFR1 P11362 2/20 0.50
EGFR P00533 1/20 0.50
KIF11 P52732 1/20 0.47
S1PR1 P21453 1/20 0.47
NPC1 O15118 1/20 0.47
NPY5R Q15761 1/20 0.45
CCNE2 O96020 1/20 0.44
CDK4 P11802 1/20 0.44
CCND1 P24385 1/20 0.44
CCNE1 P24864 1/20 0.44
CDK2 P24941 1/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP1A2 P05177 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26548587 1.00 CYP11B2 (0.59) CYP11B2CYP11B1CYP17A1CYP19A1KDR
SCHEMBL26547979 0.95 CYP11B2 (0.61) CYP11B2CYP11B1CYP17A1CYP19A1KDR
SCHEMBL26548403 0.95 CYP11B2 (0.61) CYP11B2CYP11B1CYP17A1CYP19A1KDR
SCHEMBL26548584 0.91 CYP11B2 (0.63) CYP11B2CYP11B1CYP17A1CYP19A1KDR
SCHEMBL26548895 0.91 CYP11B2 (0.63) CYP11B2CYP11B1CYP17A1CYP19A1KDR
SCHEMBL26548713 0.90 CYP11B2 (0.51) CYP11B2CYP11B1CYP17A1CYP19A1KDR
SCHEMBL15649790 0.87 KDR (0.59) KDRDGAT1KCNH2FGFR1EGFR
SCHEMBL26553161 0.87 CYP11B2 (0.49) CYP11B2CYP11B1CYP17A1CYP19A1KDR
SCHEMBL26549063 0.87 CYP2A6 (0.55) CYP11B2CYP11B1CYP17A1CYP19A1KDR
SCHEMBL26547967 0.86 CYP11B2 (0.65) CYP11B2CYP11B1CYP17A1CYP19A1KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 CYP11B2 1913/4885CYP11B1 1676/4885CYP17A1 1147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.