Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647011 | 0.92 | CA1 (0.63) | CA1CA2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2654385 | 0.92 | CA1 (0.63) | CA1CA2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL16767423 | 0.82 | RAB9A (0.61) | CA1CA2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7560695 | 0.79 | CA1 (0.47) | CA1CA2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2647028 | 0.79 | HAO1 (0.52) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL7560701 | 0.78 | GCGR (0.48) | CA1CA2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1790000 | 0.78 | ALDH1A1 (0.59) | CA1CA2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2949436 | 0.78 | ALDH1A1 (0.59) | CA1CA2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2944396 | 0.78 | ALDH1A1 (0.59) | CA1CA2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22453473 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296942-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | Novo Nordisk A/S (DK) | 2003-04-02 | — | — | EP | disclosed |
| WO-2002000612-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2002-01-03 | — | — | WO | disclosed |