Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27329663 | 0.79 | HTR2C (0.34) | — | |
| SCHEMBL20460995 | 0.78 | PDCD1 (0.36) | NUDT1 | |
| SCHEMBL27054804 | 0.74 | ROCK2 (0.39) | — | |
| SCHEMBL30775297 | 0.74 | LRRK2 (0.40) | — | |
| SCHEMBL2928676 | 0.74 | — | — | |
| SCHEMBL20053882 | 0.70 | LRRK2 (0.30) | — | |
| SCHEMBL31587569 | 0.70 | — | — | |
| SCHEMBL27637765 | 0.69 | — | — | |
| SCHEMBL21652590 | 0.68 | MAP4K1 (0.34) | — | |
| SCHEMBL30564287 | 0.68 | LRRK2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023196975-A1 | COMPOUNDS THAT INTERACT WITH RAS SUPERFAMILY PROTEINS FOR TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES, AND FIBROTIC DISEASE | SHY THERAPEUTICS, LLC (US) | 2023-10-12 | — | — | WO | disclosed |