SCHEMBL26549080

SCHEMBL26549080

FC(F)(F)c1ccc(-c2ccc3cc(-c4ccc(-c5cccc6cccnc56)cc4)cnc3c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 4/20 0.51
PDGFRB P09619 3/20 0.41
PDGFRA P16234 3/20 0.41
TRPV1 Q8NER1 2/20 0.40
SLC40A1 Q9NP59 3/20 0.40
GAK O14976 1/20 0.40
PDE4A P27815 1/20 0.39
PDE4B Q07343 1/20 0.39
PDE4C Q08493 1/20 0.39
PDE4D Q08499 1/20 0.39
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39
RAB9A P51151 1/20 0.39
NFKBIA P25963 1/20 0.39
RELA Q04206 1/20 0.39
PARP1 P09874 1/20 0.38
ESR2 Q92731 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
MAP4K4 O95819 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26549374 1.00 TOP1 (0.51) TOP1PDGFRBPDGFRATRPV1SLC40A1
SCHEMBL26549084 0.93 TOP1 (0.44) TOP1PDGFRBPDGFRASLC40A1GAK
SCHEMBL26549379 0.93 TOP1 (0.44) TOP1PDGFRBPDGFRASLC40A1GAK
SCHEMBL26549243 0.91 TOP1 (0.47) TOP1PDGFRBPDGFRATRPV1SLC40A1
SCHEMBL26548008 0.89 TOP1 (0.56) TOP1TRPV1SLC40A1PDE4APDE4B
SCHEMBL26548419 0.89 TOP1 (0.56) TOP1TRPV1SLC40A1PDE4APDE4B
SCHEMBL26569004 0.88 TOP1 (0.40) TOP1GAKPARP1
SCHEMBL26548923 0.88 TOP1 (0.54) TOP1TRPV1SLC40A1PDE4APDE4B
SCHEMBL26548602 0.88 TOP1 (0.54) TOP1TRPV1SLC40A1PDE4APDE4B
SCHEMBL26549078 0.87 TOP1 (0.47) TOP1PDGFRBPDGFRASLC40A1GAK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 TOP1 1472/4885PDGFRB 4867/4885PDGFRA 4853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.