SCHEMBL26549243

SCHEMBL26549243

FC(F)(F)c1ccc(-c2ccc3cc(-c4ccc(-c5cccc6cccnc56)nc4)cnc3c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 4/20 0.47
TRPV1 Q8NER1 2/20 0.40
ALOX5AP P20292 1/20 0.38
FEN1 P39748 1/20 0.38
PDGFRB P09619 1/20 0.38
PDGFRA P16234 1/20 0.38
SLC40A1 Q9NP59 3/20 0.37
PDE4A P27815 1/20 0.37
PDE4B Q07343 1/20 0.37
PDE4C Q08493 1/20 0.37
PDE4D Q08499 1/20 0.37
GAK O14976 1/20 0.37
CYP2A6 P11509 1/20 0.36
NFKBIA P25963 1/20 0.36
RELA Q04206 1/20 0.36
MET P08581 1/20 0.36
NPC1 O15118 1/20 0.36
POLB P06746 1/20 0.36
RAB9A P51151 1/20 0.36
PARP1 P09874 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26549247 0.93 TOP1 (0.41) TOP1TRPV1ALOX5APFEN1SLC40A1
SCHEMBL26548218 0.92 TOP1 (0.49) TOP1TRPV1ALOX5APFEN1SLC40A1
SCHEMBL26548730 0.91 TOP1 (0.48) TOP1TRPV1ALOX5APFEN1SLC40A1
SCHEMBL26549374 0.91 TOP1 (0.51) TOP1TRPV1PDGFRBPDGFRASLC40A1
SCHEMBL26549080 0.91 TOP1 (0.51) TOP1TRPV1PDGFRBPDGFRASLC40A1
SCHEMBL26549241 0.88 TOP1 (0.44) TOP1PDGFRBPDGFRAGAKCYP2A6
SCHEMBL26549245 0.86 GAK (0.38) PDGFRBPDGFRAGAKCYP2A6NPC1
SCHEMBL26559189 0.86 CYP2A6 (0.39) PDGFRBPDGFRAPDE4AGAKCYP2A6
SCHEMBL26549200 0.85 PDGFRB (0.39) TOP1TRPV1PDGFRBPDGFRAGAK
SCHEMBL26548220 0.84 TOP1 (0.43) TOP1TRPV1ALOX5APFEN1SLC40A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 TOP1 1472/4885TRPV1 885/4885ALOX5AP 2457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.