SCHEMBL26549229

SCHEMBL26549229

FC(F)(F)c1ccc(-c2ccc3cc(-c4ccc(-c5ccncc5)nc4)cnc3c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 7/20 0.51
PDGFRA P16234 7/20 0.51
GAK O14976 1/20 0.51
KIF11 P52732 1/20 0.49
EGFR P00533 1/20 0.46
MAP4K4 O95819 1/20 0.42
CDK8 P49336 1/20 0.42
CLK2 P49760 1/20 0.42
CDK7 P50613 1/20 0.42
CDK9 P50750 1/20 0.42
CDK5 Q00535 1/20 0.42
ACVR1 Q04771 1/20 0.42
ROCK1 Q13464 1/20 0.42
DYRK1A Q13627 1/20 0.42
LRRK2 Q5S007 1/20 0.42
CLK4 Q9HAZ1 1/20 0.42
DYRK1B Q9Y463 1/20 0.42
ESR2 Q92731 1/20 0.41
KDM1A O60341 1/20 0.40
MAOB P27338 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26549315 0.95 ESR2 (0.45) PDGFRBPDGFRAGAKKIF11CDK9
SCHEMBL26549232 0.93 GAK (0.49) PDGFRBPDGFRAGAKKIF11EGFR
SCHEMBL26549359 0.92 PDGFRB (0.59) PDGFRBPDGFRAGAKKIF11EGFR
SCHEMBL26549066 0.92 PDGFRB (0.59) PDGFRBPDGFRAGAKKIF11EGFR
SCHEMBL26548203 0.91 KIF11 (0.56) PDGFRBPDGFRAKIF11MAP4K4CDK8
SCHEMBL26549311 0.90 PDGFRB (0.45) PDGFRBPDGFRAGAKKIF11ESR2
SCHEMBL26549314 0.90 PDGFRB (0.45) PDGFRBPDGFRAGAKKIF11ESR2
SCHEMBL26548717 0.89 KIF11 (0.54) PDGFRBPDGFRAKIF11MAP4K4CDK8
SCHEMBL26549319 0.88 IDO1 (0.42) PDGFRBPDGFRAGAKKIF11ESR2
SCHEMBL26549220 0.88 CYP2A6 (0.51) PDGFRBPDGFRAGAKKIF11EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 PDGFRB 4867/4885PDGFRA 4853/4885GAK 3896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.