SCHEMBL26549280

SCHEMBL26549280

FC(F)(F)c1cc(-c2ccc3cc(-c4ccc(-c5cccc6c5oc5ncccc56)nc4)cnc3c2)cc(C(F)(F)F)c1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MET P08581 2/20 0.34
CCNT1 O60563 1/20 0.34
CCNA2 P20248 1/20 0.34
CDK2 P24941 1/20 0.34
CDK9 P50750 1/20 0.34
GRIN2B Q13224 8/20 0.33
GRIN1 Q05586 7/20 0.33
TOP1 P11387 2/20 0.33
MAOB P27338 1/20 0.33
TGFBR1 P36897 1/20 0.32
MTOR P42345 2/20 0.32
GAK O14976 1/20 0.31
PGR P06401 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26549278 0.94 TOP1 (0.38) METCCNT1CCNA2CDK2CDK9
SCHEMBL26548277 0.93 MAOB (0.36) METCCNT1CCNA2CDK2CDK9
SCHEMBL26548796 0.92 MAOB (0.35) METCCNT1CCNA2CDK2CDK9
SCHEMBL26549128 0.92 TOP1 (0.35) METCCNT1CCNA2CDK2CDK9
SCHEMBL26549412 0.92 TOP1 (0.35) METCCNT1CCNA2CDK2CDK9
SCHEMBL26549274 0.88 ALOX5 (0.37) METCCNT1CCNA2CDK2CDK9
SCHEMBL26549277 0.87 PDGFRB (0.37) METCCNT1CCNA2CDK2CDK9
SCHEMBL26548268 0.86 TOP1 (0.39) CCNT1CCNA2CDK2CDK9TOP1
SCHEMBL26549279 0.86 GAK (0.35) METTGFBR1GAK
SCHEMBL26549124 0.85 TOP1 (0.41) METCCNT1CCNA2CDK2CDK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 MET 4438/4885CCNT1 589/4885CCNA2 2147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.