Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 10/20 | 0.50 |
| ▸ | PPARA | Q07869 | 5/20 | 0.50 |
| ▸ | GCGR | P47871 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | GCG | P01275 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652102 | 0.86 | PPARD (0.49) | PPARDPPARAGCGRPPARGROCK2 | |
| SCHEMBL2652879 | 0.85 | PPARD (0.47) | PPARDPPARAGCGRPPARGROCK2 | |
| SCHEMBL2652593 | 0.85 | MEN1 (0.57) | GCGRFFAR4FFAR1EPHX2 | |
| SCHEMBL2653326 | 0.85 | MEN1 (0.57) | GCGRFFAR4FFAR1EPHX2 | |
| SCHEMBL2653225 | 0.84 | MEN1 (0.46) | PPARDPPARAGCGRROCK2ROCK1 | |
| SCHEMBL2653591 | 0.82 | EPHX2 (0.56) | PPARDPPARAGCGRFFAR1EPHX2 | |
| SCHEMBL2655721 | 0.82 | MEN1 (0.56) | GCGRFFAR4FFAR1EPHX2 | |
| SCHEMBL2651906 | 0.82 | MEN1 (0.56) | GCGRFFAR4FFAR1EPHX2 | |
| SCHEMBL2652659 | 0.82 | PPARD (0.52) | PPARDPPARAGCGRPPARGROCK2 | |
| SCHEMBL2654850 | 0.81 | GCGR (0.53) | PPARDPPARAGCGRPPARGGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758859-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005118542-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-12-15 | — | — | WO | disclosed |