Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 3/20 | 0.33 |
| ▸ | TK2 | O00142 | 1/20 | 0.32 |
| ▸ | TK1 | P04183 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23734278 | 0.88 | ALDH1A1 (0.43) | ALDH1A1CYP2C19SMN1; SMN2METHTT | |
| SCHEMBL18858876 | 0.85 | MET (0.39) | ALDH1A1CYP2C19SMN1; SMN2METGRIA1 | |
| SCHEMBL22381003 | 0.78 | ALDH1A1 (0.43) | ALDH1A1CYP2C19SMN1; SMN2DAOTK1 | |
| SCHEMBL24235951 | 0.77 | SMN1; SMN2 (0.58) | ALDH1A1CYP2C19SMN1; SMN2METGRIA1 | |
| SCHEMBL4484823 | 0.77 | GAA (0.51) | ALDH1A1CYP2C19SMN1; SMN2METGRIA1 | |
| SCHEMBL10137841 | 0.74 | SMN1; SMN2 (0.41) | ALDH1A1CYP2C19SMN1; SMN2METHTT | |
| SCHEMBL17379726 | 0.73 | UPP1 (0.41) | CYP2C19SMN1; SMN2GRIA1GRIA2GRIA3 | |
| SCHEMBL16434593 | 0.72 | GRIA1 (0.41) | ALDH1A1CYP2C19GRIA1GRIA2GRIA3 | |
| SCHEMBL24564759 | 0.70 | SMN1; SMN2 (0.42) | ALDH1A1CYP2C19SMN1; SMN2METHTT | |
| SCHEMBL22327058 | 0.69 | CYP2C19 (0.37) | ALDH1A1CYP2C19SMN1; SMN2METJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230332184-A1 | TEMPLATE GUIDE RNA MOLECULES | FLAGSHIP PIONEERING INNOVATIONS VI, LLC | 2023-10-19 | — | — | US | disclosed |