Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | ACP1 | P24666 | 3/20 | 0.61 |
| ▸ | GBA1 | P04062 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26552819 | 0.84 | GBA1 (0.59) | MAPTACP1GBA1TSHRMAPK1 | |
| SCHEMBL21664227 | 0.84 | MAPT (0.58) | MAPTACP1GBA1TSHRMAPK1 | |
| SCHEMBL26561064 | 0.80 | LMNA (0.54) | MAPTGBA1LMNAHTT | |
| Methane SCHEMBL11391821 | 0.79 | ACP1 (0.67) | MAPTACP1GBA1TSHRMAPK1 | |
| SCHEMBL26550810 | 0.78 | TSHR (0.60) | MAPTACP1GBA1TSHRMAPK1 | |
| SCHEMBL4089260 | 0.77 | ACP1 (1.00) | MAPTACP1TSHRMAPK1HSD17B10 | |
| SCHEMBL11184213 | 0.77 | GBA1 (0.64) | MAPTACP1GBA1TSHRMAPK1 | |
| SCHEMBL1084122 | 0.76 | ACP1 (1.00) | MAPTACP1TSHRMAPK1HSD17B10 | |
| SCHEMBL1083859 | 0.76 | ACP1 (1.00) | MAPTACP1TSHRMAPK1HSD17B10 | |
| SCHEMBL21664313 | 0.75 | GBA1 (0.57) | MAPTACP1GBA1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3551188-B1 | SUBSTITUTED QUINAZOLINE SULFONAMIDES AS THIOREDOXIN INTERACTING PROTEIN (TXNIP) INHIBITORS | SOUTHERN RES INST (US) | 2023-10-18 | — | — | EP | disclosed |