⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26554458 | 0.81 | DRD2 (0.30) | — | |
| SCHEMBL14156706 | 0.79 | P2RY2 (0.43) | — | |
| SCHEMBL26554372 | 0.76 | LMNA (0.36) | — | |
| SCHEMBL26554384 | 0.74 | MEN1 (0.41) | — | |
| SCHEMBL26554401 | 0.74 | — | — | |
| SCHEMBL26554377 | 0.72 | SLC28A1 (0.33) | — | |
| SCHEMBL26554402 | 0.72 | SLC28A1 (0.33) | — | |
| SCHEMBL25697911 | 0.71 | LGALS9 (0.37) | — | |
| SCHEMBL17465413 | 0.71 | HPSE (0.37) | — | |
| SCHEMBL17357650 | 0.71 | HPSE (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365970-A1 | Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof | ALIGOS THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | US | disclosed |
| US-20230332153-A1 | Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof | ALIGOS THERAPEUTICS, INC. (US) | 2023-10-19 | — | — | US | disclosed |