Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.47 |
| ▸ | PGK1 | P00558 | 1/20 | 0.47 |
| ▸ | PGK2 | P07205 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18041228 | 0.91 | ADORA3 (0.65) | ADORA3ADORA1ADORA2BPGK1PGK2 | |
| SCHEMBL29363191 | 0.91 | ADORA3 (0.65) | ADORA3ADORA1ADORA2BPGK1PGK2 | |
| SCHEMBL25844194 | 0.91 | ADORA3 (0.52) | ADORA3ADORA1ADORA2BPGK1PGK2 | |
| SCHEMBL18061792 | 0.91 | ADORA3 (0.65) | ADORA3ADORA1ADORA2BPGK1PGK2 | |
| SCHEMBL25204813 | 0.91 | ADORA3 (0.65) | ADORA3ADORA1ADORA2BPGK1PGK2 | |
| SCHEMBL12202862 | 0.87 | ADORA2A (0.48) | ADORA3ADORA1ADORA2BPGK1PGK2 | |
| SCHEMBL9569366 | 0.86 | ADORA3 (0.66) | ADORA3ADORA1ADORA2BPGK1PGK2 | |
| SCHEMBL26780511 | 0.86 | ADORA3 (0.66) | ADORA3ADORA1ADORA2BPGK1PGK2 | |
| SCHEMBL26039175 | 0.86 | ADORA3 (0.66) | ADORA3ADORA1ADORA2BPGK1PGK2 | |
| SCHEMBL12202684 | 0.85 | ADORA2A (0.46) | ADORA3ADORA1ADORA2BPGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | Atea Pharmaceuticals, Inc. (US) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | NUDT1, PNP, ATIC | ADORA3 59/4885ADORA1 30/4885ADORA2B 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.