Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2656142 | 0.88 | MEN1 (0.57) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2656759 | 0.87 | HPGD (0.54) | HPGDNPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL14223786 | 0.87 | LMNA (0.61) | HPGDNPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL14194995 | 0.81 | PPARA (0.48) | HPGDNPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL2656267 | 0.80 | NPC1 (0.56) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1565655 | 0.77 | HSPA5 (0.52) | HPGDNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL2656595 | 0.76 | NPC1 (0.56) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27652020 | 0.75 | RAB9A (0.74) | HPGDNPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL1564841 | 0.74 | CYP1A2 (0.55) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12858465 | 0.73 | GCK (0.74) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125735-A2 | 2,2,2-TRI-SUBSTITUTED ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | Advinus Therapeutics Private Limited (IN) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008104994-A2 | 2,2,2-TRI-SUBSTITUTED ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2008-09-04 | — | — | WO | disclosed |