Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26564593 | 1.00 | FAAH (0.44) | FAAHTRPV1ALDH1A1CNR1CNR2 | |
| SCHEMBL26564628 | 0.98 | ALDH1A1 (0.41) | FAAHTRPV1ALDH1A1CNR1CNR2 | |
| SCHEMBL26564597 | 0.92 | ALDH1A1 (0.35) | FAAHTRPV1ALDH1A1CNR1CNR2 | |
| SCHEMBL26564600 | 0.84 | — | — | |
| SCHEMBL26564577 | 0.83 | ALDH1A1 (0.45) | FAAHTRPV1ALDH1A1CNR1CNR2 | |
| SCHEMBL26564632 | 0.77 | ALDH1A1 (0.39) | TRPV1ALDH1A1CNR1CNR2 | |
| SCHEMBL27953101 | 0.73 | FAAH (0.56) | FAAHTRPV1GMNNUSP2LMNA | |
| SCHEMBL9869904 | 0.73 | FAAH (0.56) | FAAHTRPV1GMNNUSP2LMNA | |
| SCHEMBL24218814 | 0.72 | FAAH (0.74) | FAAHTRPV1GMNNUSP2LMNA | |
| SCHEMBL23040322 | 0.72 | FAAH (0.74) | FAAHTRPV1GMNNUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331657-A1 | NANOMATERIALS COMPRISING ESTER-LINKED ACETALS | BEAM THERAPEUTICS INC. | 2023-10-19 | — | — | US | disclosed |
| US-20230331656-A1 | NANOMATERIALS COMPRISING ACETALS | BEAM THERAPEUTICS INC. | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331657-A1 | NANOMATERIALS COMPRISING ESTER-LINKED ACETALS | LIPA, SGMS1, SGMS2 | FAAH 668/4885TRPV1 4757/4885ALDH1A1 331/4885 |
| US-20230331656-A1 | NANOMATERIALS COMPRISING ACETALS | SGMS1, SGMS2, LIPA | FAAH 1525/4885TRPV1 4509/4885ALDH1A1 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.