Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24335773 | 0.86 | ALDH1A1 (0.54) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL18572523 | 0.83 | KCNMA1 (0.63) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL24335251 | 0.83 | ALDH1A1 (0.51) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL24335776 | 0.82 | ALDH1A1 (0.50) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1351165 | 0.81 | ALDH1A1 (0.64) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL24335250 | 0.81 | ALDH1A1 (0.49) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL30705054 | 0.81 | ALDH1A1 (0.49) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6724526 | 0.81 | ALDH1A1 (0.56) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5989871 | 0.80 | CDC25B (0.56) | KMT2AMEN1CNR1CNR2POLB | |
| SCHEMBL24335456 | 0.80 | ALDH1A1 (0.60) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331663-A1 | SMALL MOLECULE NICOTINAMIDE ADENINE DINUCLEOTIDE MODULATORS | THE CLEVELAND CLINIC FOUNDATION | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331663-A1 | SMALL MOLECULE NICOTINAMIDE ADENINE DINUCLEOTIDE MODULATORS | NQO1, NADK, CD38 | ALDH1A1 158/4885LMNA 1685/4885SMN1; SMN2 2057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.