Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.56 |
| ▸ | CNR2 | P34972 | 13/20 | 0.54 |
| ▸ | CNR1 | P21554 | 8/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5990471 | 0.82 | CDC25B (0.56) | CDC25BCNR2CNR1CYP2C9POLB | |
| SCHEMBL9856908 | 0.81 | CDC25B (0.59) | CDC25BCNR2CNR1CYP2C9POLB | |
| SCHEMBL26565632 | 0.80 | ALDH1A1 (0.58) | CNR2CNR1POLBMEN1KMT2A | |
| SCHEMBL5991233 | 0.79 | PPARG (0.56) | POLBMEN1KMT2A | |
| SCHEMBL30785075 | 0.79 | PPARG (0.56) | POLBMEN1KMT2A | |
| SCHEMBL5990230 | 0.78 | MAOB (0.46) | — | |
| SCHEMBL5490326 | 0.77 | CDC25B (0.50) | CDC25BCNR2CNR1CYP2C9KMT2A | |
| SCHEMBL5990023 | 0.76 | NAMPT (0.55) | CNR2CNR1 | |
| SCHEMBL5077492 | 0.75 | ALDH1A1 (0.61) | CNR2CNR1CYP2C9MEN1KMT2A | |
| SCHEMBL11527165 | 0.75 | MAPT (0.48) | CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |