Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498212 | 0.89 | CYP1A2 (0.42) | KMT2ACYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL13819771 | 0.87 | TAAR1 (0.40) | ESR1ESR2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL13819785 | 0.87 | TAAR1 (0.40) | ESR1ESR2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL23139239 | 0.81 | ALDH1A1 (0.38) | KMT2ACYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL1498213 | 0.81 | ALDH1A1 (0.38) | KMT2ACYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL13430004 | 0.80 | MME (0.36) | KMT2AMMETAAR1SIGMAR1 | |
| SCHEMBL24294405 | 0.80 | SLC6A2 (0.48) | ESR1ESR2TAAR1POLBCTDSP1 | |
| SCHEMBL15562967 | 0.79 | SIGMAR1 (0.49) | TAAR1SIGMAR1HTR2ASLC6A4 | |
| SCHEMBL23139181 | 0.79 | ALDH1A1 (0.39) | KMT2ACYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL13819786 | 0.78 | APP (0.46) | CYP1A2CYP2D6MMETAAR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023198901-A1 | NOVEL SUBSTITUTED 4-AMINO-4-OXO-BUT-2-ENYL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2023-10-19 | — | — | WO | disclosed |