Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13819771 | 0.95 | TAAR1 (0.40) | TAAR1HTR2AMMESIGMAR1SLC6A4 | |
| SCHEMBL26565775 | 0.87 | KMT2A (0.42) | TAAR1HTR2AMMESIGMAR1SLC6A4 | |
| SCHEMBL13819786 | 0.86 | APP (0.46) | TAAR1HTR2AMMESIGMAR1SLC6A4 | |
| SCHEMBL1498212 | 0.84 | CYP1A2 (0.42) | SIGMAR1KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL28376724 | 0.80 | TP53 (0.43) | TAAR1SLC6A4CYP2A6ACACBALDH1A1 | |
| SCHEMBL13430004 | 0.80 | MME (0.36) | TAAR1MMESIGMAR1ALDH1A1APP | |
| SCHEMBL6771848 | 0.79 | SIGMAR1 (0.41) | TAAR1HTR2AMMESIGMAR1IDO1 | |
| SCHEMBL6684808 | 0.77 | TAAR1 (0.38) | TAAR1HTR2AMMESIGMAR1CYP2A6 | |
| SCHEMBL3865414 | 0.77 | SLC18A3 (0.42) | TAAR1MMESIGMAR1ACACBESR1 | |
| SCHEMBL23139239 | 0.77 | ALDH1A1 (0.38) | SIGMAR1KDM4EALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051246-B2 | Compound having trimethylene structure, polymer compound containing unit that has trimethylene structure, and reactive compound having trimethylene structure | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2015-06-09 | — | — | US | disclosed |
| US-20120289674-A1 | COMPOUND HAVING TRIMETHYLENE STRUCTURE, POLYMER COMPOUND CONTAINING UNIT THAT HAS TRIMETHYLENE STRUCTURE, AND REACTIVE COMPOUND HAVING TRIMETHYLENE STRUCTURE | KANAGAWA UNIVERSITY (JP) | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289674-A1 | COMPOUND HAVING TRIMETHYLENE STRUCTURE, POLYMER COMPOUND CONTAINING UNIT THAT HAS TRIMETHYLENE STRUCTURE, AND REACTIVE COMPOUND HAVING TRIMETHYLENE STRUCTURE | SUV39H2, SUV39H1, EZH1 | TAAR1 421/4885HTR2A 1252/4885MME 4599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.